The Circadian
Supplement Thesis.
Your body is not the same at 7am and 11pm. Its hormones, enzymes, and cellular machinery operate on a 24-hour cycle. Most supplement brands ignore this completely.
NOVA was built on one idea: timing is as important as the ingredients themselves. What you take matters. When you take it matters more.
Why Timing Matters
Your circadian rhythm governs cortisol, melatonin, core body temperature, heart rate variability, and cognitive performance — all on predictable 24-hour cycles. Cortisol peaks naturally between 6–9am to provide energy and alertness. Melatonin rises after sunset to initiate sleep. Ignoring these signals doesn't make you immune to them.
RISE works with your morning cortisol peak to sharpen focus and drive without overstimulation. REST works with your evening cortisol decline to accelerate the transition to deep sleep and maximize overnight repair. This is chronobiology applied to supplementation — and it's why NOVA is two products, not one.
RISE
Seven ingredients. Each at a clinical, evidence-based dose. No proprietary blends — you see exactly what you're taking, and why.
Caffeine Anhydrous
150mgAdenosine receptor antagonist. Caffeine blocks adenosine — the compound that builds up during wakefulness and causes fatigue — preventing it from signaling tiredness to the brain. At 150mg, we hit the sweet spot for cognitive enhancement without overstimulation.
[Nehlig A. Is caffeine a cognitive enhancer? Journal of Alzheimer's Disease. 2010.]
L-Theanine
200mgAlpha-brainwave promoter. L-Theanine promotes alpha wave activity — the brainwave state associated with calm focus — while modulating GABA and glutamate pathways to reduce anxiety without sedation. The 2:1 Theanine:Caffeine ratio is the most studied cognitive stack in existence.
[Haskell CF et al. Effects of L-theanine, caffeine and their combination on cognition. Biological Psychology. 2008.]
Lion's Mane Extract
500mgNerve Growth Factor stimulator. Lion's Mane contains hericenones and erinacines that cross the blood-brain barrier and stimulate synthesis of Nerve Growth Factor (NGF). NGF is critical for neuroplasticity, neuron survival, and long-term cognitive function.
[Mori K et al. Improving effects of the mushroom Yamabushitake on mild cognitive impairment. Phytotherapy Research. 2009.]
Alpha-GPC
300mgCholinergic precursor. Alpha-GPC directly increases brain levels of acetylcholine — the neurotransmitter responsible for memory, learning, and attention. Unlike choline bitartrate, Alpha-GPC has high bioavailability and rapid blood-brain barrier penetration.
[Tamura Y et al. Effects of alpha-glycerylphosphorylcholine on memory and attention. Nutrients. 2021.]
Rhodiola Rosea
200mgAdaptogenic cortisol modulator. Rhodiola acts on the HPA axis to normalize cortisol output under stress — reducing fatigue, improving mood, and enhancing resistance to physical and mental stressors. Classified by the European Medicines Agency as a well-established adaptogen.
[Darbinyan V et al. Rhodiola rosea in stress induced fatigue. Phytomedicine. 2000.]
REST
Designed for the window between dinner and sleep. Every ingredient chosen for what your body needs during evening wind-down and overnight recovery.
L-Glycine
3000mgCore body temperature regulator. Research shows glycine lowers core body temperature by dilating blood vessels near the skin surface — which is the primary physiological trigger for sleep onset. This mechanism is completely distinct from sedation.
[Bannai M, Kawai N. New therapeutic strategy: glycine improves sleep quality. Journal of Pharmacological Sciences. 2012.]
Magnesium Glycinate
400mgGABA receptor modulator. Magnesium is a cofactor for GABA synthesis and directly modulates NMDA receptors to reduce neural excitation. Deficiency is strongly associated with insomnia and anxiety. Glycinate has the highest bioavailability with the least GI side effects.
[Abbasi B et al. The effect of magnesium supplementation on primary insomnia in elderly. Journal of Research in Medical Sciences. 2012.]
Ashwagandha KSM-66
600mgHPA axis regulator. KSM-66 is the most clinically studied ashwagandha extract. Multiple double-blind, placebo-controlled trials show it reduces serum cortisol by up to 30% within 60 days. Lower cortisol at night is directly associated with faster sleep onset and better deep sleep quality.
[Chandrasekhar K et al. Safety and efficacy of high-concentration ashwagandha root extract. Indian Journal of Psychological Medicine. 2012.]
Tart Cherry Extract
480mgNatural melatonin precursor + anti-inflammatory. Tart cherries are one of the few natural food sources of melatonin. The anthocyanins also demonstrate COX-2 inhibitory properties — reducing post-exercise inflammation and accelerating overnight muscle recovery.
[Howatson G et al. Effect of tart cherry juice on melatonin levels and sleep quality. European Journal of Nutrition. 2012.]
Apigenin
50mgGABA-A receptor partial agonist. Apigenin (the active compound in chamomile) binds to benzodiazepine sites on GABA-A receptors — promoting anxiolysis and sedation without the dependency or tolerance associated with pharmaceutical sleep aids.
[Zanoli P et al. Behavioral characterization of the flavonoids apigenin and chrysin. Fitoterapia. 2000.]
How We Make It
Third-Party Tested
Every batch is independently verified for purity and potency by an ISO-accredited third-party lab before it ships.
Health Canada Eligible
NOVA is formulated to meet Natural Health Product (NHP) standards — the most rigorous supplement framework in North America.
No Proprietary Blends
Every ingredient and its exact dose is listed on the label. No hiding behind "blends." No guessing.
Zero Fillers
No maltodextrin, no artificial colors, no silica. The label is the formula — nothing more.
See The Full Formulas
Everything above, in a single morning and evening stick pack.
Build Your System